756400login-checkAntibiotic Combo for Acute Infection Cleared of Kidney Risk |
— Use of cefepime meanwhile resulted in more neurological dysfunction
By Michele Sullivan
BOSTON — In adults hospitalized for acute infections, cefepime and piperacillin-tazobactam turned out to be equally safe in terms of serious kidney outcomes, although the latter antibiotic showed a lower risk for coma and delirium, an open-label randomized trial found.
Cefepime versus piperacillin-tazobactam for suspected infection resulted in no significant difference in the study’s primary endpoint, the highest stage of acute kidney injury (AKI) or death at 14 days (OR 0.95, 95% CI 0.80-1.13, P=0.56), Edward Qian, MD, of Vanderbilt University Medical Center in Nashville, Tennessee, reported here during a late-breaking abstract session at IDWeek. Read the full article in MedPage Today.
756400login-checkAntibiotic Combo for Acute Infection Cleared of Kidney Risk |