Post-Transplant Diabetes Risk Informed by Polygenic Risk Profiles in Donors, Recipients

NEW YORK – Taking organ donor and recipient genetics into consideration — via a polygenic risk score (PRS) — may help identify individuals at risk of developing diabetes after a solid organ transplant.

“Our study demonstrates the importance, and the potential application, of PRS in solid organ transplantation,” co-first and corresponding author Abraham Shaked, a researcher at the University of Pennsylvania’s Penn Transplant Institute, and his coauthors wrote in Nature Medicine on Thursday. Read the story in GenomeWeb here.