CDC Cuts Booster Interval for the Immunocompromised

The CDC updated its interim guidance on COVID-19 vaccination to give immunocompromised people a shorter wait for their booster shot.

It is now recommended that people who are moderately or severely immunocompromised receive a booster 3 months — down from 5 months previously — after the third dose of an mRNA vaccine, for a total of four doses. Previewed at last week’s meeting of the Advisory Committee on Immunization Practices (ACIP), this change was attributed to concern about the immune response and loss of mRNA protection over time for these patients.
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