{"id":7371,"date":"2023-09-18T07:19:00","date_gmt":"2023-09-18T14:19:00","guid":{"rendered":"https:\/\/allocare.caredx.com\/?p=7371"},"modified":"2023-09-14T07:21:42","modified_gmt":"2023-09-14T14:21:42","slug":"hcv-infection-once-a-hurdle-to-heart-transplantation-is-now-manageable","status":"publish","type":"post","link":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/indexphp\/post\/2023\/09\/18\/hcv-infection-once-a-hurdle-to-heart-transplantation-is-now-manageable\/","title":{"rendered":"HCV Infection, Once a Hurdle to Heart Transplantation, Is Now Manageable"},"content":{"rendered":"<span class=\"simplefavorite-button has-count loading\" data-postid=\"7371\" data-siteid=\"1\" data-groupid=\"1\" data-favoritecount=\"0\" style=\"\">Loading<span class=\"sf-icon-spinner-wrapper\"><i class=\"sf-icon-spinner\"><\/i><\/span><\/span>\n<p>By Peter Wehrwein, Managing Editor<br><em><br>The advent of the direct-acting antivirals, such as Harvoni (ledipasvir and sofosbuvir) means people can be treated for HCV infection if they receive a heart from an HCV-viremic donor, according to a recent review paper. The supply of hearts available for transplantation has increased, partly because HCV-viremic individuals are now part of the donor pool.<\/em><\/p>\n\n\n\n<p>Transplanting organs, including hearts, from people infected with hepatitis C virus (HCV) used to be avoided because of the risk of infection and studies showing that the recipients had worse outcomes,<\/p>\n\n\n\n<p>Marina Nunez, M.D., Ph.D., of Wake Forest School of Medicine, co-wrote a review paper exploring the hepatitis C infection and heart transplantation.<\/p>\n\n\n\n<p>But when the direct-acting antivirals against hepatitis C started to come on the market, particularly\u00a0<a href=\"https:\/\/www.gilead.com\/-\/media\/files\/pdfs\/medicines\/liver-disease\/harvoni\/harvoni_patient_pi.pdf\">Harvoni<\/a>\u00a0(ledipasvir and sofosbuvir) in 2014, the views and practices changed. <a href=\"https:\/\/www.managedhealthcareexecutive.com\/view\/hcv-infection-once-a-barrier-to-heart-transplantation-is-now-manageable\">Read more <\/a>in Managed Healthcare Executive.<\/p>\n<span class=\"simplefavorite-button has-count loading\" data-postid=\"7371\" data-siteid=\"1\" data-groupid=\"1\" data-favoritecount=\"0\" style=\"\">Loading<span class=\"sf-icon-spinner-wrapper\"><i class=\"sf-icon-spinner\"><\/i><\/span><\/span>","protected":false},"excerpt":{"rendered":"<p>Loading By Peter Wehrwein, Managing EditorThe advent of the direct-acting antivirals, such as Harvoni (ledipasvir and sofosbuvir) means people can be treated for HCV infection if they receive a heart &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/indexphp\/post\/2023\/09\/18\/hcv-infection-once-a-hurdle-to-heart-transplantation-is-now-manageable\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;HCV Infection, Once a Hurdle to Heart Transplantation, Is Now Manageable&#8221;<\/span><\/a><\/p>\n","protected":false},"author":208,"featured_media":4372,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":0,"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[45,5],"tags":[2285,1180],"post_format":[],"Dislikes":"","Likes":"","simplefavorites_count":"","views":"1137","post_likes_plusCounter":"","post_dislikes_plusCounter":"","acf":[],"_links":{"self":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/7371"}],"collection":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/users\/208"}],"replies":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/comments?post=7371"}],"version-history":[{"count":1,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/7371\/revisions"}],"predecessor-version":[{"id":7372,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/7371\/revisions\/7372"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media\/4372"}],"wp:attachment":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media?parent=7371"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/categories?post=7371"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/tags?post=7371"},{"taxonomy":"post_format","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/post_format?post=7371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}