{"id":5838,"date":"2022-11-27T07:52:00","date_gmt":"2022-11-27T15:52:00","guid":{"rendered":"https:\/\/allocare.caredx.com\/?p=5838"},"modified":"2022-11-21T10:55:55","modified_gmt":"2022-11-21T18:55:55","slug":"study-uncovers-mechanism-behind-primary-graft-dysfunction-2","status":"publish","type":"post","link":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/indexphp\/post\/2022\/11\/27\/study-uncovers-mechanism-behind-primary-graft-dysfunction-2\/","title":{"rendered":"Study uncovers mechanism behind primary graft dysfunction"},"content":{"rendered":"<span class=\"simplefavorite-button has-count loading\" data-postid=\"5838\" data-siteid=\"1\" data-groupid=\"1\" data-favoritecount=\"0\" style=\"\">Loading<span class=\"sf-icon-spinner-wrapper\"><i class=\"sf-icon-spinner\"><\/i><\/span><\/span>\n<p>Northwestern Medicine scientists have discovered the pathways through which autoantibodies\u2014immune proteins that mistakenly attack a person&#8217;s own body\u2014leak out of blood vessels and cause primary graft dysfunction in some lung transplant recipients, according to findings published in the\u00a0<em>Journal of Clinical Investigation<\/em>\u00a0(<em>JCI<\/em>).<\/p>\n\n\n\n<p>Primary\u00a0<a href=\"https:\/\/medicalxpress.com\/tags\/graft\/\">graft<\/a>\u00a0dysfunction (PGD) is a potentially lethal injury to fragile transplanted lungs that occurs in the first days after a transplant operation and affects more than half of\u00a0<a href=\"https:\/\/medicalxpress.com\/tags\/lung\/\">lung<\/a>\u00a0transplant recipients. The condition is the leading cause of early post-transplantation morbidity and mortality. <a href=\"https:\/\/medicalxpress.com\/news\/2022-11-uncovers-mechanism-primary-graft-dysfunction.html\">Read more <\/a>from Medical Xpress.<\/p>\n<span class=\"simplefavorite-button has-count loading\" data-postid=\"5838\" data-siteid=\"1\" data-groupid=\"1\" data-favoritecount=\"0\" style=\"\">Loading<span class=\"sf-icon-spinner-wrapper\"><i class=\"sf-icon-spinner\"><\/i><\/span><\/span>","protected":false},"excerpt":{"rendered":"<p>Loading Northwestern Medicine scientists have discovered the pathways through which autoantibodies\u2014immune proteins that mistakenly attack a person&#8217;s own body\u2014leak out of blood vessels and cause primary graft dysfunction in some &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/indexphp\/post\/2022\/11\/27\/study-uncovers-mechanism-behind-primary-graft-dysfunction-2\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Study uncovers mechanism behind primary graft dysfunction&#8221;<\/span><\/a><\/p>\n","protected":false},"author":208,"featured_media":3899,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":0,"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[45,8],"tags":[541,1333,1290],"post_format":[],"Dislikes":"","Likes":"","simplefavorites_count":"","views":"1213","post_likes_plusCounter":"2","post_dislikes_plusCounter":"","acf":[],"_links":{"self":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/5838"}],"collection":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/users\/208"}],"replies":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/comments?post=5838"}],"version-history":[{"count":1,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/5838\/revisions"}],"predecessor-version":[{"id":5839,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/5838\/revisions\/5839"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media\/3899"}],"wp:attachment":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media?parent=5838"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/categories?post=5838"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/tags?post=5838"},{"taxonomy":"post_format","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/post_format?post=5838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}