{"id":5797,"date":"2022-11-18T08:07:15","date_gmt":"2022-11-18T16:07:15","guid":{"rendered":"https:\/\/allocare.caredx.com\/?p=5797"},"modified":"2022-11-18T08:07:31","modified_gmt":"2022-11-18T16:07:31","slug":"study-uncovers-mechanism-behind-primary-graft-dysfunction","status":"publish","type":"post","link":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/indexphp\/post\/2022\/11\/18\/study-uncovers-mechanism-behind-primary-graft-dysfunction\/","title":{"rendered":"Study Uncovers Mechanism Behind Primary Graft Dysfunction"},"content":{"rendered":"<span class=\"simplefavorite-button has-count loading\" data-postid=\"5797\" data-siteid=\"1\" data-groupid=\"1\" data-favoritecount=\"3\" style=\"\">Loading<span class=\"sf-icon-spinner-wrapper\"><i class=\"sf-icon-spinner\"><\/i><\/span><\/span>\n<p>Northwestern Medicine scientists have discovered the pathways through which autoantibodies \u2013 immune proteins that mistakenly attack a person\u2019s own body \u2013 leak out of blood vessels and cause primary graft dysfunction in some lung transplant recipients, according to findings&nbsp;<a href=\"https:\/\/www.jci.org\/articles\/view\/157975\">published<\/a>&nbsp;in the&nbsp;<em>Journal of Clinical Investigation<\/em>&nbsp;(JCI).<\/p>\n\n\n\n<p>Primary graft dysfunction (PGD) is a potentially lethal injury to fragile transplanted lungs that occurs in the first days after a transplant operation and affects more than half of lung transplant recipients. The condition is the leading cause of early post-transplantation morbidity and mortality. <a href=\"https:\/\/news.feinberg.northwestern.edu\/2022\/11\/17\/study-uncovers-mechanism-behind-primary-graft-dysfunction\/\">Read the full article<\/a> from Northwestern Medicine News Center.<\/p>\n<span class=\"simplefavorite-button has-count loading\" data-postid=\"5797\" data-siteid=\"1\" data-groupid=\"1\" data-favoritecount=\"3\" style=\"\">Loading<span class=\"sf-icon-spinner-wrapper\"><i class=\"sf-icon-spinner\"><\/i><\/span><\/span>","protected":false},"excerpt":{"rendered":"<p>Loading Northwestern Medicine scientists have discovered the pathways through which autoantibodies \u2013 immune proteins that mistakenly attack a person\u2019s own body \u2013 leak out of blood vessels and cause primary &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/indexphp\/post\/2022\/11\/18\/study-uncovers-mechanism-behind-primary-graft-dysfunction\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Study Uncovers Mechanism Behind Primary Graft Dysfunction&#8221;<\/span><\/a><\/p>\n","protected":false},"author":208,"featured_media":3899,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":0,"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[45,8],"tags":[374,1289],"post_format":[],"Dislikes":"","Likes":"","simplefavorites_count":"3","views":"1221","post_likes_plusCounter":"4","post_dislikes_plusCounter":"","acf":[],"_links":{"self":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/5797"}],"collection":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/users\/208"}],"replies":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/comments?post=5797"}],"version-history":[{"count":1,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/5797\/revisions"}],"predecessor-version":[{"id":5798,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/5797\/revisions\/5798"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media\/3899"}],"wp:attachment":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media?parent=5797"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/categories?post=5797"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/tags?post=5797"},{"taxonomy":"post_format","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/post_format?post=5797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}