{"id":3635,"date":"2021-10-29T09:19:00","date_gmt":"2021-10-29T16:19:00","guid":{"rendered":"https:\/\/allocare.caredx.com\/?p=3635"},"modified":"2022-08-16T14:13:20","modified_gmt":"2022-08-16T21:13:20","slug":"common-gene-variant-may-predict-peritoneal-dialysis-outcomes","status":"publish","type":"post","link":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/indexphp\/post\/2021\/10\/29\/common-gene-variant-may-predict-peritoneal-dialysis-outcomes\/","title":{"rendered":"Common Gene Variant May Predict Peritoneal Dialysis Outcomes"},"content":{"rendered":"<span class=\"simplefavorite-button has-count loading\" data-postid=\"3635\" data-siteid=\"1\" data-groupid=\"1\" data-favoritecount=\"1\" style=\"\">Loading<span class=\"sf-icon-spinner-wrapper\"><i class=\"sf-icon-spinner\"><\/i><\/span><\/span>\n<p>&#8220;A common genetic variant predicted poor outcomes from peritoneal dialysis, suggesting a potential factor for patient selection and treatment, researchers found.<\/p>\n\n\n\n<p>Variants in&nbsp;<em>AQP1<\/em>, the gene that encodes for a key water transport channel across the peritoneal membrane, were associated with decreased ultrafiltration while on peritoneal dialysis and a 70% increased risk of death or failure of that form of dialysis as well.<\/p>\n\n\n\n<p>The 10-16% of patients with the TT genotype of the rs2075574 variant could be good candidates for precision medicine in dialysis treatment, Johann Morelle, MD, PhD, of the Cliniques Universitaires Saint-Luc in Brussels, Belgium, and colleagues reported in the\u00a0<em>New England Journal of Medicine<\/em>.&#8221;<\/p>\n\n\n\n<p>Read more <a href=\"https:\/\/www.medpagetoday.com\/nephrology\/esrd\/95155?xid=nl_mpt_DHE_2021-10-21&amp;eun=g1917319d0r&amp;utm_source=Sailthru&amp;utm_medium=email&amp;utm_campaign=Daily%20Headlines%20Top%20Cat%20HeC%20%202021-10-21&amp;utm_term=NL_Daily_DHE_dual-gmail-definition\">here<\/a>.<\/p>\n<span class=\"simplefavorite-button has-count loading\" data-postid=\"3635\" data-siteid=\"1\" data-groupid=\"1\" data-favoritecount=\"1\" style=\"\">Loading<span class=\"sf-icon-spinner-wrapper\"><i class=\"sf-icon-spinner\"><\/i><\/span><\/span>","protected":false},"excerpt":{"rendered":"<p>Loading &#8220;A common genetic variant predicted poor outcomes from peritoneal dialysis, suggesting a potential factor for patient selection and treatment, researchers found. Variants in&nbsp;AQP1, the gene that encodes for a &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/indexphp\/post\/2021\/10\/29\/common-gene-variant-may-predict-peritoneal-dialysis-outcomes\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Common Gene Variant May Predict Peritoneal Dialysis Outcomes&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":3636,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":0,"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[912,2],"tags":[38,18,214],"post_format":[],"Dislikes":"","Likes":"","simplefavorites_count":"1","views":"1507","post_likes_plusCounter":"1","post_dislikes_plusCounter":"","acf":[],"_links":{"self":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/3635"}],"collection":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/comments?post=3635"}],"version-history":[{"count":1,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/3635\/revisions"}],"predecessor-version":[{"id":3637,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/3635\/revisions\/3637"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media\/3636"}],"wp:attachment":[{"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media?parent=3635"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/categories?post=3635"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/tags?post=3635"},{"taxonomy":"post_format","embeddable":true,"href":"https:\/\/app-allocare-wordpress-linux-prod.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/post_format?post=3635"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}