vaccine – Page 2

August 1, 2021July 30, 2021

Immunocompromised to unvaccinated: You’re still a community

3 Clark County women hope unvaccinated people stop and consider those who are at high risk of serious complications from COVID-19

“As people across the United States continue to flout the COVID-19 vaccine and cases of the delta variant surge, those living with compromised immune systems have a dire plea: consider the safety of others.

Jennifer Browning, Nicole Arneson and Laura Ellsworth are three friends living in Clark County who have all had kidney transplants. For them, life during the pandemic means strictly following the same COVID measures mandated for the general public before a vaccine ever became available.

“We don’t do the things that vaccinated people are doing and because we’ve been told by our medical providers that you need to continue to live as if you’ve been unvaccinated,” said Ellsworth.”

Watch the interview here.

July 23, 2021July 23, 2021

CDC advisory committee voices support for immunocompromised people getting boosters

During the last year and a half, immunocompromised people have been at extremely high risk for the virus. And for many, the COVID vaccine didn’t change that.

That’s why a group of independent Centers for Disease Control and Prevention experts at a Thursday meeting largely voiced support for allowing immunocompromised people to talk to their doctors about getting a third shot, a booster, that could increase their antibody response to vaccines.

What Evidence Do We Need to Move Forward With COVID Boosters?

“More data and an evaluation of several factors at home and abroad are key.

On Monday, employees of Pfizer met with high level executives in the Biden administration to discuss the role of boosters — a.k.a. a third vaccination with an mRNA vaccine for SARS-CoV-2. Some have speculated that, as with the first two doses, the emergency use authorization pathway will again be used to market boosters. With the rise of the Delta variant and others, enthusiasm in the media and the Twitter commentariat for boosters is growing. However, there are certain criteria that must be met before we jump on the booster bandwagon. Some of these criteria apply at home, and others apply abroad.”

Learn more, here.

July 14, 2021July 13, 2021

Q&A: Transplant Patient Immune Response to COVID-19 Vaccines

CareDx and the Lung Transplant Foundation hosted the “COVID-19 Vaccines and the Latest Data on Immune Response in Transplant Recipients” webinar on May 12, 2021. More than 1,000 transplant recipients, caregivers, and clinicians tuned in to the live webinar to hear the latest research on the immune response of transplant recipients to the COVID-19 vaccine.

Dorry Segev, MD, PhD, a transplant surgeon from Johns Hopkins Medicine, and one of the authors of a recently published study in the Journal of the American Medical Association (JAMA) that looked at the antibody response in more than 650 transplant patients, presented findings and answered questions.

Below is a summary of some of the questions posed during the session.

Read the full Q&A, here.

May 21, 2021May 21, 2021

Transplant patients, some others with immune issues, stuck in limbo as country reopens

Maria Hoffman feels as though she has been left behind. Her adopted hometown of Charleston, S.C., is hopping – with restaurants and bars fully open, park concerts in full swing and maskless friends reuniting with hugs on streets.

Hoffman, 39, is fully vaccinated and eager to rejoin the world. But as a kidney transplant patient, she is hesitant to participate for fear of becoming infected. “Risk is very different for people in my situation,” she said. “I am 100% acting like I am not immunized.”

The state worker is among millions of immunocompromised Americans, about 3 to 4% of the U.S. population, for whom the shots may not work fully, or at all, and who are unsure of their place in a country that is increasingly opening up. Emerging research shows that 15 to 80% of those with certain conditions, such as specific blood cancers or who have had organ transplants, are generating few antibodies.

Read the full story, here.

April 21, 2021August 16, 2022

First COVID-19 Vaccine Dose Elicits Weak Antibody Response in Most KTRs

“Most adult kidney transplant recipients (KTRs) exhibit a weak antibody response to the first injection of the Moderna mRNA COVID-19 vaccine, according to the findings of a prospective study published in Kidney International.¹

“We already know that kidney transplant recipients tend to respond less well to vaccines because of the immunosuppression, but data concerning the anti-SARS-CoV-2 antibody response after COVID-19 vaccine in this population were lacking,” said first author Ilies Benotmane, MD, of Strasbourg University Hospital and the Fédération de Médecine Translationnelle (FMTS) in Strasbourg, France.

COVID-19 vaccine distribution programs worldwide have given priority to immunocompromised patients, including KTRs. Vaccination was recommended, however, for this patient population even though KTRs were not included in the vaccine clinical trials. Dr Benotmane and colleagues conducted a preliminary study investigating the efficacy and safety of the Moderna mRNA-1273 vaccine in KTRs by looking at the anti SARS CoV-2 antibody response after the first injection.”

Immunocompromised And Concerned About The Vaccine? Here’s What You Need To Know

“Lots of people have questions about getting vaccinated against COVID-19. That includes the millions of Americans with weakened immune systems that put them at higher risk of severe disease if they do get infected with the coronavirus.

“Patients want to know whether it’s safe to get it and, if they do get it, which one should they get? And of course, they also have concerns about how it can affect their own condition as well,” says Dr. Sharon Dowell, a rheumatologist at Howard University Hospital in Washington, D.C., who says she has been getting a barrage of questions from patients lately.

People can be immunocompromised for a wide range of reasons. Some are being treated with immunosuppressive medications for conditions such as rheumatoid arthritis, lupus, Crohn’s disease or psoriasis. Others are organ transplant recipients on powerful anti-rejection medications or cancer patients receiving chemotherapy.

Dowell and other doctors say vaccinating immunocompromised patients is especially important. But it also raises special considerations that these patients should discuss with their doctor beforehand. Here’s what you need to know.”

Read the full article, here.

March 29, 2021August 16, 2022

Cancer Patients and Transplant Recipients Need Both COVID-19 Vaccine Doses

“Natural immunity and vaccine responses may be weaker in people with immune suppression, so they should get their second dose promptly

A majority of people with cancer and organ transplant recipients are capable of mounting an immune response to the SARS-CoV-2 coronavirus and can gain immunity from COVID-19 vaccines, according to recent research. But people with immune suppression may have slower and weaker responses to natural infection or vaccination, so it is especially important that they get their second dose on schedule.

People with serious immune suppression are at risk for more severe complications and death due to COVID-19. This group includes cancer patients who use immune-suppressing therapy, transplant recipients who take immunosuppressive drugs to prevent organ rejection and people with AIDS (advanced, uncontrolled HIV disease).

It is well known that immunosuppressed people can have weaker immune responses to natural infection and vaccination, but SARS-CoV-2 immunity in this population is not well understood. What’s more, cancer patients on treatment and other people with advanced immune suppression were generally excluded from COVID-19 vaccine trials (though people with well-controlled HIV could enroll).”

Read the full article, here.

March 25, 2021March 30, 2021

American Kidney Fund Applauds White House Decision to Distribute COVID-19 Vaccines Directly to ESRD Patients at Dialysis Clinics

“The American Kidney Fund (AKF) today issues the following statement in response to the Biden-Harris administration’s announcement that COVID-19 vaccines will be distributed directly to end-stage renal disease (ESRD, or kidney failure) patients at dialysis clinics:

“On behalf of the 555,000 Americans who rely on dialysis to survive, AKF is grateful to the Biden-Harris administration for announcing its plans to distribute COVID-19 vaccines directly to ESRD patients at the nation’s dialysis clinics. AKF recently met with Congressional and Biden-Harris administration officials to recommend this action. Vaccine distribution for ESRD patients at dialysis clinics will be a major step forward in protecting people with kidney failure from COVID-19 and in addressing disparities in our health care system that disproportionately impact the kidney patient community.”

Read the full article, here.

January 29, 2021March 30, 2021

The reason I qualify for a Covid-19 vaccine has nothing to do with the fact that I’m immunocompromised. That needs to change

“My cell phone rang on a Sunday afternoon in early March and I answered it immediately. It was my friend, a doctor who specializes in epidemiology and infectious diseases. She warned me that the coronavirus was about to surge in New York City and recommended that if I could flee the city and retreat to my parents’ house, I should do it, and fast.

I hung up the phone, called my parents, rented a car, packed my bags and drove 13 hours from New York City to the suburbs of Chicago the next morning. Meanwhile, my friends were still going out to dinner and going into work. I could tell my coworkers and roommate thought I was being absurd, but I couldn’t afford to care about their opinions. I had simply fought too hard for all 27 years of my life, I couldn’t lose it here.”

Read the full piece, here.