Gene Pierce – The Legacy of an Organ Donation, Transportation, and Transplantation Pioneer

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60 years ago, Gene Pierce was a Sunday school teacher and Boy Scout troop leader in his free time. For his day job, he worked in the marketing department at Chesapeake Pulp and Paper Mill in West Point, Virginia—where he was instrumental in developing Green Life Fertilizer.1

When Gene found out that he and his wife were expanding their family to five children, he realized he needed to make a little more money. There happened to be two job openings at the time that interested him: One at the railroad company and the other at Medical College of Virginia (MCV). Read the full story.

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How does your heart work?

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“The heart is a strong and muscular organ that is about the size of a fist in adults. It pumps blood throughout the body and is located behind the breastbone between the lungs. Deoxygenated blood flows from the heart to the lungs where it gives up carbon dioxide and is freshly oxygenated. From there, the blood returns to the heart and is pumped to the rest of the body.”

Learn more from UNOS, here.

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How the kidney works

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“Your kidneys play a vital role in balancing the amount of fluid in your body, detecting waste in your blood, and knowing when to release the vitamins, minerals, and hormones you need to stay alive. They do this by disposing of waste products and turning them into urine.”

Lear more from UNOS here.

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How does your liver work?

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“The liver has many functions that are necessary for life. The liver helps process carbohydrates, fats and proteins, and stores vitamins. It processes nutrients absorbed from food in the intestines and turns them into materials that the body needs for life.

For example, the liver makes the factors that the blood needs for clotting. It also secretes bile to help digest fats, and breaks down toxic substances in the blood such as drugs and alcohol. The liver is also responsible for the metabolism of most drugs.”

Learn more from UNOS here.

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How do your lungs work?

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“When you breathe, you transport oxygen to the body’s cells to keep them working and clear your system of the carbon dioxide that this work generates. The lungs take in air from the atmosphere and provide a place for oxygen to enter the blood and for carbon dioxide to leave the blood. The lungs are divided into sections, with three on the right and two on the left.”

Learn more from UNOS here.

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Heart Transplant: A Slightly More Level Playing Field Under New UNOS System

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“Recent changes to U.S. donor heart allocation were followed by a narrowing of racial disparities in listing and transplant, though much more work remains to eliminate inequality, researchers warned.

Black patients listed for cardiac transplantation in 2011-2020 were less likely than white peers to die while waiting (adjusted HR 0.88, 95% CI 0.78-0.98). However, they ultimately had lower odds of undergoing transplant (adjusted HR 0.87, 95% CI 0.84-0.90) and a higher risk of post-transplant death (adjusted HR 1.14, 95% CI 1.04-1.24), reported P. Elliott Miller, MD, of Yale School of Medicine in New Haven, Connecticut, and colleagues.”

Read more, here.

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U.S. on pace to top 40,000 transplants in a single year for first time

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“In just the first half of 2021, 21,061 organ transplants have been performed in the U.S. according to data from United Network for Organ Sharing (UNOS), which serves as the Organ Procurement and Transplantation Network under federal contract.

Organ donation from deceased donors is up 15% over last year. There were 900 more deceased donors — people who provided one or more organs to save and enhance the lives of others — between January 1 and June 30 of 2021 than there were during the same period in 2020. The drop in donors caused by the pandemic beginning in the middle of March last year was offset enough by high numbers early in the year that there were still 242 more donors in the first half of 2020 than in the first half of 2019.

Organ transplants from deceased donors are also up — by 11%. A total of 17,821 deceased donor transplants were performed in the U.S. in the first half of 2021 compared to 15,933 in the first six months of last year. 2020 marked the 10th consecutive record breaking year for organ donation from deceased donors and the 8th in a row for deceased donor transplants.”

Read more, here.

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Equity means providing a transplant for every single patient that needs one

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“Recently, I joined UNOS President-Elect Jerry McCauley, M.D. at a meeting organized by the National Academies of Sciences, Engineering and Medicine (NASEM) focused on equity. We were honored to share UNOS’ work in this space and lend our voices to this vital national discussion – a discussion we look forward to continuing.

UNOS is acutely attuned to issues of equity. As the mission-driven non-profit serving as the nation’s transplant system, we work with our community partners to ensure equitable policies and outcomes in multiple ways, including:”

Read the full article, here.

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Making allocation more fair and flexible

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“The organ donation and transplantation system in the U.S. has never worked better than it does today. Deceased donor transplants have increased for 10 consecutive years, and 26% more organ transplants are performed today than five years ago. But every day, we work to continuously improve and make the system even more effective and efficient to serve all of the patients waiting for a lifesaving transplant.

As part of these efforts, the organ donation and transplant community is working together to introduce a more fair and flexible approach to allocating donated organs to get the right organ to the right patient at the right time. Our policies have always been data-driven, but this new approach applies advanced analytic techniques to create an algorithm that makes every factor in the match run comparable.

Called continuous distribution, this new framework moves organ allocation from placing and considering patients by classifications to considering multiple factors all at once using an overall score. Doing so will dissolve hard boundaries that exist in the current, category-based system and ensure that no single factor determines a patient’s priority on the waiting list.

Read more, here.

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Post-transplant health & wellness webinar (part 2)

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Health and wellness continues long after receiving an organ transplant. Learn about post-transplant health from UNOS Medical Director David Klassen, M.D., Filza Hussain, M.D., of Stanford University, and Koren Axelrod of CareDx. This is the third webinar in our Transplantation Journey series.

Watch the webinar, here.

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