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Balanced Crystalloid Fluids Surpass Saline for Kidney Transplant

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ORLANDO, Florida — Using a low-chloride, balanced crystalloid solution for all intravenous (IV) fluids received by patients who received a deceased donor kidney transplant resulted in significantly fewer episodes of delayed graft function compared with patients who received saline as their IV fluids, in a new multicenter trial with 807 randomized and evaluable patients called BEST-Fluids.

“The findings suggest that balanced crystalloids should be the standard-of-care IV fluid in deceased donor kidney transplantations,” said Michael G. Collins, MBChB, PhD, at Kidney Week 2022, organized by the American Society of Nephrology. Read the full story in Medscape here.

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The transplant patient who got two second chances

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George Surratt felt like the luckiest man in the world when he got a liver transplant. The wait list for an organ is so long that some patients run out of time.
 
And, so, nine years later, when the Maplewood, MN, engineer turned again to University of Minnesota doctors, this time for a kidney transplant, he was worried.
 
Could lightning strike twice and allow him to join his wife in watching their two kids grow into careers and maybe even families? Read the full story from University of Minnesota News.

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Kidney Transplant Rejection: What You Need to Know

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Since the first kidney transplant more than 60 years ago,1 doctors have developed a deeper understanding of how to protect donated organs. With newer medications and improved management, it’s less likely transplanted kidneys will undergo rejection by the immune system.

That’s not to say doctors have completely eliminated the risk of kidney transplant rejection, though. Unfortunately, while many kidneys will last much longer, the median life of a kidney transplant is still only ten years. Understanding the risks and early warning signs of rejection gives you the best chance of a successful kidney transplant.

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Multi-state models preferable to measure graft risk among kidney transplant recipients

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Compared with the Kaplan-Meier estimator, researchers found multi-state models provided a more accurate and comprehensive assessment of the life course and graft risk of older kidney transplant recipients.

“As a result of excellent graft survival in older patients and, inevitably, relatively high mortality, most older kidney recipients can expect to die with a functioning graft. Also noteworthy is the fact that there is an increased rate of early graft failure in elderly patients, at least in part due to higher use of expanded criteria kidneys in this age group,” Thomas Vanhove, MD, PhD, from Massachusetts General Hospital at Harvard Medical School in Boston, and colleagues wrote. Read more in Healio.

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Patient Preferences for Choices in Kidney Transplant Examined

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MONDAY, Aug. 22, 2022 (HealthDay News) — Patients are willing to receive a worse-quality kidney sooner in order to avoid additional waiting time for transplant, according to a study published online Aug. 19 in the Clinical Journal of the American Society of Nephrology.

Sanjay Mehrota, Ph.D., from Northwestern University in Evanston, Illinois, and colleagues used a discrete-choice experiment that presented a deceased donor kidney to 605 patients who are waiting for or have received a kidney transplant. Read more in Physician’s Weekly.

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Doctor donates kidney to patient

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Transplant nephrologist was perfect match for patient-turned-friend.

It’s rare that a transplant nephrologist becomes a kidney donor — but that’s exactly what happened to Dr. Aji Djamali last month.

Not long into his journey to becoming a nephrologist and surgeon, Djamali knew he wanted to donate his kidney. With the rare blood type B, he knew he could make an ideal match for a patient one day. Read or watch the story from ABC News here.

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She helped her husband get a kidney. Now, their foundation helps others with their transplant needs.

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While most people flinch when asked to fundraise, Jackie Hutz, 60, of Butler, embraces it. “That’s one of the gifts I have. It’s easy for me, and I know it’s not easy for other people.”

After spending weeks or months planning and hosting a Night at the Races, craft show or a popular purse bash, she has no trouble giving away the proceeds to those on the receiving or giving end of organ transplantation. “Until every person on the transplant list can receive an organ in a timely manner,” she said, “I will continue to do the wildest and craziest events to raise awareness and funds.” Read the full story in the Pittsburgh-Post Gazette.

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Nonprofit aims to help veterans requiring kidney transplants

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No veteran should die waiting for a kidney transplant. However, as of the July 4th weekend, there were 1,781veterans across the United States on a waiting list. Sharyn Kreitzer is on a mission to eradicate the wait.

Three years ago, Kreitzer founded the nonprofit Donor Outreach for Veterans, or DOVE. Her mission is to locate living kidney donors for higher risk patients.
Read the full story in MilitaryTimes.

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