Simplifying Diagnosis of Rejection After Kidney Transplant

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By Nancy A. Melville

An automated system for the diagnosis of rejection after kidney transplant simplifies the assessment of increasingly complex criteria, significantly reducing the common occurrence of misclassification and potentially improving outcomes, according to new research.

“To date, no study in transplantation and other medical fields has developed and validated an automated multimodal disease classification,” report the French authors in their article published online May 4 in Nature Medicine.
Read more in Medscape.

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Algorithm may help avoid 40% of kidney transplant rejection misdiagnoses: study

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By Nick Paul Taylor

Dive Brief:

  • An algorithm could help pathologists avoid 40% of misdiagnoses of organ transplant rejection and improve patient risk stratification, according to a paper published in Nature Medicine.
  • The decision-support system automatically diagnoses the status of kidney transplants based on the criteria physicians use to determine if a patient is rejecting an organ. Applied to two clinical trials, the algorithm reclassified rejection diagnoses made by pathologists.
    Read the full article in MedTech Dive.
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Kidney Transplant Rejection: What You Need to Know

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Since the first kidney transplant more than 60 years ago,1 doctors have developed a deeper understanding of how to protect donated organs. With newer medications and improved management, it’s less likely transplanted kidneys will undergo rejection by the immune system.

That’s not to say doctors have completely eliminated the risk of kidney transplant rejection, though. Unfortunately, while many kidneys will last much longer, the median life of a kidney transplant is still only ten years. Understanding the risks and early warning signs of rejection gives you the best chance of a successful kidney transplant.

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Kidney Transplant Rejection: What You Need to Know

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Since the first kidney transplant more than 60 years ago,1 doctors have developed a deeper understanding of how to protect donated organs. With newer medications and improved management, it’s less likely transplanted kidneys will undergo rejection by the immune system.

That’s not to say doctors have completely eliminated the risk of kidney transplant rejection, though. Unfortunately, while many kidneys will last much longer, the median life of a kidney transplant is still only ten years. Understanding the risks and early warning signs of rejection gives you the best chance of a successful kidney transplant. Read the full story on CareDx.com.

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