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Six-Month Survival Following Heart Transplant After Donor Circulatory Death Is Noninferior to Transplant After Donor Brain Death

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By Luke Halpern

Notably, donor hearts from those who underwent circulatory death were able to be preserved and analyzed in situ.

Survival at 6 months after transplantation with a donor heart that was reanimated and assessed after circulatory-death was found to be noninferior to patient survival among recipients of the standard care transplantation using a donor heart that had been preserved in cold storage after brain-death, according to the results of a new study published in The New England Journal of Medicine. The more in Pharmacy Times.

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Reanimated hearts work as well for transplants and could make more organs available for patients in need, study finds

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By Brenda Goodman, CNN

Researchers say they have been able to tap a new pool of organ donors to preserve and transplant their hearts: people whose hearts have stopped beating, resulting in so-called circulatory death.

Traditionally, the only people considered to be suitable organ donors were those who have been declared brain-dead but whose hearts and other organs have continued to function.
Read the full story in CNN.

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Does New Heart Transplant Method Challenge Definition of Death?

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By Sue Hughes
The relatively recent innovation of heart transplantation after circulatory death of the donor is increasing the number of donor hearts available and leading to many more lives on the heart transplant waiting list being saved. Experts agree it’s a major and very welcome advance in medicine.

However, some of the processes involved in one approach to donation after circulatory death has raised ethical concerns and questions about whether they violate the “dead donor rule” — a principle that requires patients be declared dead before removal of life-sustaining organs for transplant.
Read the full article in Medscape.

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