Cell therapy shows promise for improving gas exchange in COPD, may offer potential cure

Loading

By Isabella Hornick

Patients with COPD who underwent autologous transplantation of lung progenitor cells had improved gas exchange capacity, quality of life and walking distance, according to study results.

Further, these results, presented at European Respiratory Society International Congress, showed that transplant of these P63+ progenitor cells repaired lung damage in those with mild emphysema.
Read more from Healio.

Loading

Fixed-ratio spirometry misses COPD diagnoses in African American patients

Loading

By Isabella Hornick

A fixed-ratio criteria of FEV1/FVC less than 0.7 for COPD resulted in fewer diagnoses in African American vs. non-Hispanic white individuals, according to results published inJournal of General Internal Medicine.

“Relying only on spirometry for diagnosing COPD does not do justice to the known manifestations of the disease,” Elizabeth A. Regan, MD, PhD, professor of medicine at National Jewish Health, told Healio. Read the full article in Healio.

Loading

COPD raises risk for type 2 myocardial infarction-related hospitalizations, worse outcomes

Loading

NASHVILLE, Tenn. — People with COPD have a greater risk for type 2 myocardial infarction-related admissions and worse in-hospital outcomes, researchers reported at the CHEST Annual Meeting.

Type 2 myocardial infarction occurs due to a mismatch in myocardial oxygen supply and demand. COPD is known to cause increased myocardial oxygen supply and demand mismatch. However, the extent of that mismatch is not clearly delineated,” Brian Brereton, MBBS, clinical fellow in internal medicine at Jersey General Hospital, United Kingdom, told Healio. Read the article in Healio.

Loading

Proactive, virtual intervention improves quality of life after discharge for COPD exacerbation

Loading

A pragmatic health system-level intervention improved quality of life for patients discharged after COPD exacerbation but failed to reduce 180-day readmission or mortality, researchers reported.

“Despite national policy efforts to drive improvement, most patients discharged after COPD do not receive care known to improve health outcomes for COPD, and there is scant evidence that overall quality of care has improved,”David H. Au, MD, MS, professor in the department of medicine at the Center of Innovation for Veteran-Centered and Value-Driven Care, Seattle, and colleagues wrote in the American Journal of Respiratory and Critical Care Medicine. Read more in Healio.

Loading