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CKD, Recent Transplant May Increase Cancer Risk, Study Finds

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A population-based cohort study found that patients with chronic kidney disease (CKD) or who underwent a recent kidney transplant had a higher risk of cancer compared with people with normal kidney function.

A study published in American Journal of Kidney Diseases found that the risk of cancer was higher in patients with mild to moderate chronic kidney disease (CKD) and in kidney transplant recipients vs patients with normal kidney function. Patients with kidney disease also had a higher risk of cancer-related mortality.
Read more in the American Journal of Managed Care (AJMC).

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Lifestyle Effects Intervention in Chronic Kidney Disease Patients

Photo by Arek Adeoye on Unsplash
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Patients with chronic kidney disease (CKD) may benefit considerably from supervised lifestyle therapies that increase physical activity and fitness. For a study, researchers conducted a randomized clinical study in 160 patients with stage 3–4 CKD to test the efficacy of a lifestyle intervention in improving cardiorespiratory fitness and exercise capacity over 36 months. Read more in Physician’s Weekly.

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Cancer risk increased for patients with mild to moderate CKD, kidney transplant recipients

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Patients with mild to moderate chronic kidney disease or recipients of kidney transplants are at increased risk for cancer, according to data published in the American Journal of Kidney Disease.

“We sought to characterize the burden of cancer diagnoses and cancer deaths among patients with kidney disease and determine whether their risk was increased vs. patients with normal kidney function,” Abhijat Kitchlu, MD, MSc, a staff nephrologist and clinician investigator at the University Health Network and an assistant professor of medicine at the University of Toronto, told Healio. “We also assessed whether patients with kidney disease were found to have more advanced cancer stage when they were diagnosed.”
Read the full story in Healio.

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7 Self-Care Tips for Chronic Kidney Disease

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Chronic kidney disease (CKD) is a progressive health condition that damages your kidneys. Your kidneys are two bean-shaped organs that help remove waste and excess fluid from the body.

High blood pressure and diabetes are the leading causes of CKD. Treating these conditions can help slow the progression of kidney damage. If your kidney function gets too low, you may need dialysis or a kidney transplant. Read more.

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Malnutrition risk correlates with kidney function decline, CKD among older adults

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Malnutrition is associated with poor kidney function, increased risk of kidney function decline and chronic kidney disease among older adults without advanced kidney disease, according to data published in the Journal of Renal Nutrition.

Further, researchers noted that physicians might consider using preventative interventions to lower malnutrition risk (MR) among patients in this population. Read more.

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Risk Factors for Chronic Kidney Disease

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Chronic kidney disease is defined as damage of the renal parenchyma that results in chronic deterioration of kidney function and may result in progression to end-stage renal disease. It is a non-communicable disease that includes a range of physiological disorders which are attributed to abnormal renal function and its progressive decline infiltration rate (the glomerular filtration rate).

There are five stages of kidney damage in chronic kidney disease that range from mild kidney dysfunction to complete failure. The burden of chronic kidney disease is increasing worldwide and is becoming increasingly prevalent in developing countries. Overall, the prevalence is estimated to be between 8 and 16% worldwide. Patients who have stage three or four chronic kidney disease are at a higher risk of progressing to either end-stage renal disease or death. Read more.

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How a Low-Protein Diet Can Delay Dialysis in Patients With Chronic Kidney Disease

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At any given time, an estimated 15% of the US adult population has chronic kidney disease (CKD). It manifests as reduced kidney function to below 60% of its normal range (estimated glomerular filtration rate < 60 mL/min/1.73 m2) or by spillage of protein into the urine. The many causes of CKD include diabetes, hypertension, glomerulonephritis, and cystic kidney diseases. CKD is an irreversible malady with no known cure, and it invariably worsens over time. CKD is associated with higher mortality risks as it advances. If the patient does not die of cardiovascular or infectious events, end-stage renal disease ensues and the patient requires maintenance dialysis therapy or kidney transplantation to survive.
Read more.

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