By Mark E. Neumann
AWAK Technologies has received a breakthrough device designation from the FDA for its progression prediction model directed at patients with chronic kidney disease, according to a press release. Read the article in Healio.
By Tarun Sai Lomte
In a recent study published in the Journal of Internal Medicine, researchers observe that kidney transplantation (KT) mitigates the effects of renal aging.
Chronic kidney disease (CKD) is an age-related disease and exhibits an accelerated aging phenotype. The reduced clearance of uremic toxins during CKD results in the accumulation of toxic solutes that contribute to endothelial dysfunction, chronic inflammatory burden, and increased oxidative stress. Read the full article in News Medical Life Sciences.
By Shawn M. Carter
Slow walking pace and weight gain may be linked to chronic kidney disease risk in adults who have obesity but not diabetes, according to a study by Drexel University researchers.
Results from the College of Medicine and Dornsife School of Public Health suggest staying fit and avoiding weight gain may be more pivotal than weight loss alone to reduce CKD risk.
Read the full article in Healio.
By Shawn M. Carter
Psychological distress may be linked to poor self-management of chronic kidney disease, according to a recently published study of patients with CKD who were not on dialysis.
“Beginning with the diagnosis of chronic kidney disease (CKD) onward, patients are confronted with profound changes that require extensive emotional skills. An additional burden is adhering to disease self-management recommendations,” lead researcher Cinderella K. Cardol, PhD, of the health, medical and neuropsychology unit at Leiden University in The Netherlands, and colleagues wrote. Read the full article in Healio.
By Mark E. Neumann
One goal of the Advancing American Kidney Health initiative, which was launched in 2019, was to significantly increase the number of kidney transplants.
The way to do that, according to CMS at the time, was to intervene early and slow chronic kidney disease progression so preemptive transplants could be performed, allowing patients to forgo dialysis.
Read the full story in Healio.
By Scott Buzby
Concomitant chronic kidney disease and diabetes was prognostic of all-cause death and MI within 3 years among women undergoing drug-eluting stent implantation, according to new data. Read the full article in Healio.
By Shannon Firth
Physicians and advocates explored ways to improve access to clinical trials, dialysis, and transplants for racial and ethnic minorities with chronic kidney disease during a webinaropens in a new tab or window hosted by U.S. News & World Report and sponsored by the American Kidney Fund (AKF).
When the COVID-19 pandemic struck, people with chronic kidney disease, particularly those in kidney failure, could not isolate the way other people could because they needed to go to dialysis or other medical appointments, explained LaVarne Burton, president and CEO of the AKF.
Read the full article in MedPage Today.
By Dr. Priyom Bose, PhD
Around 10% of the global population is affected by chronic kidney disease (CKD). The risk of CKD progressing into end-stage renal disease (ESRD) is exceptionally high, which requires dialysis or kidney transplantation. At present, there is no effective treatment for CKD is available. Hence, there is an urgent need to uncover the underlying pathological mechanisms of CKD to help formulate effective treatment strategies to prevent and cure the disease. A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating CKD. Read more in News Medical Life Sciences.
Increased fat mass, particularly visceral adiposity, promotes kidney disease generation and progression through direct and indirect mechanisms, and pharmacologic treatment is necessary to avoid adverse outcomes, according to a speaker.
“The direct mechanisms that you and I treat in the office everyday are BP, cholesterol and diabetes,” Matthew Weir, MD, professor and chief of the division of nephrology at University of Maryland School of Medicine, said during a presentation at the World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease. Read more in Healio.
Chronic kidney disease, already a problem affecting millions of Americans, is only expected to become more prevalent as the country ages. For those with end-stage disease, a transplant is the ideal treatment, but dialysis is their reality. Hundreds of thousands of Americans flock to clinics three times a week to have their blood filtered through — in the absence of a functioning kidney — a machine.
As a medical treatment, dialysis is a stopgap measure that fails to fix a chronic problem (average life expectancy on dialysis is five to 10 years). As an industry, dialysis has significant flaws, including a lag in home dialysis use. Read more in STAT.