Patients with the rs2305480 variant of the GSDMB gene who had a pet dog as a baby did not have an increased risk for persistent wheeze or asthma, according to a study published in The Journal of Allergy and Clinical Immunology.
This finding occurred despite the fact that the GSDMB missense variant (G allele) of rs2305480, which is located in the 17q12-21 locus, has been associated with asthma and asthma exacerbations.
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