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Humanised mouse model identifies the best match for organ donor

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US researchers have developed a mouse model that holds promise in identifying the best organ donor and showing early signs of transplant rejection.

Researchers at the Medical College of Georgia at Augusta University, US, developed a humanised mouse model that shows great promise in identifying a patient’s best match for a living organ donor and also holds promise for recognising the earliest signs that the recipient’s immune system may start attacking that new organ. Read more in Drug Target Review.

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Social determinants of health tied to long-term employment after heart transplant

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A database analysis showed 22% of heart transplant recipients who survived to 1 year and received follow-up were employed full time at 1 year and nearly 33% were employed at 2 years after transplant.

In a retrospective analysis of more than 10,000 heart transplant recipients who survived to 1 year with follow-up, researchers also found that employment at the time of listing or transplantation was strongly associated with employment after surgery. Read the full story in Healio.

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Revised Policy Set to Improve Kidney Transplant Waitlist Time for Black Candidates

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The Board of Directors of the Organ Procurement and Transplantation Network (OPTN) has approved a mandatory waiting time adjustment for Black kidney transplant candidates disadvantaged by race-based kidney function estimates. The policy revision, which went into effect on January 5, 2023, is a major step toward kidney transplantation equity. Read more in Renal & Urology News.

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New record set for annual organ transplants in US

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The number of organs transplanted in 2022 set a new annual record at 42,887 transplants in the U.S., including more than 25,000 kidney transplants for the first time, according to a press release from the United Network of Organ Sharing.

There was an overall 3.7% increase in transplants since 2021 and a 3.4% increase in kidney transplants. Specifically, 25,498 kidney transplants were performed. Records were also set for liver, heart and lung transplants. Read more in Healio.

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New method of donor-lung distribution could decrease deaths of candidates on transplant waitlist

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A new method of donor-lung distribution is projected to decrease the number of candidate deaths who are on the waitlist for lung transplant, according to a study by Cleveland Clinic and the U.S. Scientific Registry of Transplant Recipients (SRTR) published in The American Journal of Transplantation. Read the full article in Medical Life Sciences.

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After a Lifetime of Adversity, Chelsea Roman is Thriving

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In 1984, Chelsea Roman entered the world two months early. Her mom went into labor in a parking lot. Fortunately, that parking lot was across the street from a hospital.

Chelsea’s mom walked to the hospital in severe pain, and before they could even numb her up, she endured a delivery by cesarian. Chelsea was stillborn. For the first five minutes of her life, Chelsea was not breathing. Read more about Chelsea’s transplant journey on CareDx.com.

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Italian police use Lamborghini to deliver kidneys to transplant patients

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Specially adapted supercar driven from Padua to Rome to ‘deliver the most beautiful Christmas present – life’

Italian police have used a specially adapted Lamborghini supercar to deliver two kidneys to donor patients hundreds of kilometres apart.

“Travelling on the motorway to deliver the most beautiful Christmas present – life,” they said in a statement posted on social media, alongside a picture of a medical cool box in a purpose-built compartment at the front of the Huracán.
Read the full story in The Guardian.

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