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Keto Versus Mediterranean Diet: Which Is Better for Diabetes?

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— Crossover study looked at cardiometabolic outcomes for each popular diet

Both the ketogenic and Mediterranean diets successfully cut blood sugar levels in patients with prediabetes or type 2 diabetes, according to a small randomized crossover trial.

Among 33 adults, the well-formulated ketogenic diet (WFKD) resulted in a 9% drop in HbA1c values after 12 weeks, while the Mediterranean-plus diet (Med-Plus) resulted in a 7% drop, reported Christopher Gardner, PhD, of Stanford University in California, and colleagues. Read the article in MedPage Today.

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Diabetes in Kidney Transplant Recipients Ups Risk for Overall Graft Loss

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Type 2 diabetes in kidney transplant recipients (KTRs) is associated with an increased risk for overall graft loss, with the increased risk due to death with a functioning graft, according to study findings presented at the 2022 American Transplant Congress (ATC 2022) in Boston, Massachusetts.

Vinayak Rohan, MD, of the Medical University of South Carolina in Charleston, and colleagues conducted a longitudinal study of 233,703 KTRs using 2002-2018 data from the Scientific Registry of Transplant Recipients. Read more in Renal & Urology News.

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Is Diabetes a Risk Factor for Long COVID? Possibly.

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— Mixed results in seven-study scoping review

The jury is still out as to whether diabetes is a risk factor for post-acute sequelae of COVID-19 (PASC), a researcher reported.

In a scoping review of seven studies, three (43%) concluded that diabetes was indeed a “potent” risk factor for developing long COVID following infection, according to Jessica L. Harding, PhD, of Emory University School of Medicine in Atlanta.
Read more in MedPage Today.

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Action needed to combat elevated risk for depression, suicide in diabetes

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NEW ORLEANS — Risks for depression and suicidal ideation are higher among people with vs. without diabetes, and cases of suicide are likely underreported, according to a presenter at the American Diabetes Association Scientific Sessions.

Katharine Barnard-Kelly, PhD, chief science officer at Spotlight Consultations in Portsmouth, U.K., professor at the Southern Health NHS Foundation Trust and chair of the governing committee of the FDA Reducing Suicide Rates Among Individuals with Diabetes (RESCUE) Collaborative Community, said depression, suicidal ideation and self-harm are more common among people with diabetes than many people realize, affecting both men and women as well as all age groups. Read more in Healio here.

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Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

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In a new study, a team of researchers from the University of Missouri, Georgia Tech and Harvard University has demonstrated the successful use of a novel Type 1 diabetes treatment in a large animal model. Their approach involves transplanting insulin-producing pancreas cells -; called pancreatic islets -; from a donor to a recipient, without the need of long-term immunosuppressive drugs.

In people living with Type 1 diabetes, their immune system can malfunction, causing it to attack itself, said Haval Shirwan, a professor of child health and molecular microbiology and immunology in the MU School of Medicine, and one of the study’s lead authors.
Read more in News Medical Life Science.

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Patients With Type 2 Diabetes and CKD Face Poor COVID Outcomes

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— Severity of kidney disease ups risk of ICU time, in-hospital mortality, and more

SAN DIEGO — Certain factors were highly predictive of severe COVID illness in hospitalized patients who had type 2 diabetes (T2D) and chronic kidney disease (CKD), a researcher reported.

In a single-center study of patients with T2D and CKD hospitalized with COVID-19 infection, having hyperglycemia upon admission was tied with more than a 10 times higher risk of severe COVID illness (OR 10.49, 95% CI 3.09-35.60), according to Ella Burguera-Couce, an MD candidate at the Warren Alpert Medical School of Brown University in Providence, Rhode Island. Read the complete article in MedPage Today.

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