A Missouri University of Science and Technology researcher is looking for ways artificial intelligence can improve how kidney donors are matched with recipients.
Missouri S&T engineering management assistant professor Casey Canfield is leading a research effort to develop AI software that can streamline the matching process. Read more from St. Louis Public Radio.
Adults with graft-versus-host disease who were treated with a three-drug regimen with cyclophosphamide after transplant may have improved survival rate compared with those treated with a two-drug regimen.
Patients treated with a three-drug regimen — cyclophosphamide, tacrolimus and mycophenolate mofetil — after undergoing a stem cell transplant had increased one-year graft-versus-host disease (GVHD) relapse-free survival compared with those treated with a two-drug regimen, according to findings from a phase 3 trial. Read more in Cure Today.
Healio and Cardiology Today have compiled a list of the most-read news of 2022 in cardiology.
Readers were most interested in a meta-analysis questioning the association between statin-induced LDL lowering and CV outcomes; firsts in xenotransplantation of genetically modified pig hearts; how moderate wine intake with meals may reduce type 2 diabetes risk; and more. Read the full story in Healio.
These organs that live for more than a century could raise the age of potential donors, perhaps shortening waits for the life-saving procedure
Your liver could outlive you—even into the triple-digits, new research suggests.
Using the United Network for Organ Sharing’s organ transplant database, scientists assessed the ages of 253,406 livers transplanted between 1990 and 2022. Their analysis revealed that 25 of them had survived for more than 100 years.
Read the full article in Smithsonian Magazine.
Non-compliance with immunosuppressive drugs has been reported as the most significant cause of graft loss. Since non-compliance with immunosuppressive drugs is preventable, certain approaches based on the risk factors and causes of non-compliance can help eliminate this problem.
Read the complete abstract in Cureus.
Treatment of HF has evolved rapidly in recent years, with novel therapies and a fundamentally new treatment algorithm offering options for improved management of the disease across the full spectrum of ejection fraction. Read more from Healio.
“It’s a gift of life,” says PKD survivor Judith Belair-Kyle who received a kidney transplant on Dec. 1 from a live donor after over a year of campaigning on social media. Brittany Henriques reports. Watch her story here.
by Leigh MacMillan
Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury. The findings, reported in The Journal of Clinical Investigation, identify a novel signaling pathway as a therapeutic target in chronic kidney disease progression. Read more from the VUMC Reporter.
A multinational collaborative report of global disease trends and risk factors shows CVD remains the leading cause of death and hypertension remains the leading modifiable risk factor for premature CV death worldwide, researchers reported.
Read the full story in Healio.
Report on 1st transplant in scleroderma patient predicts future success
The case of a person with scleroderma who successfully received a lung transplant from a donor who had tested positive for COVID-19 may predict positive outcomes for other patients, according to a recent report.
“To our knowledge this represents the first successful case of lung transplantation of donor lungs positive for COVID-19,” the researchers wrote. Read more in Scleroderma News.