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Response to treatment for AKI improved 90-day survival in patients waitlisted for LT

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By Kate Burba

BOSTON — Response to treatment for acute kidney injury correlated with improved 90-day survival and shorter lengths of hospital stay among patients with cirrhosis waitlisted for liver transplant, according to data at The Liver Meeting.

“[Acute kidney injury] in cirrhosis occurs commonly in hospitalized patients with cirrhosis and leads to worse outcomes,” Xing Li, MD, MBA, a third-year gastroenterology fellow at Massachusetts General Hospital, told Healio. Read the full article in Healio.

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‘Significant differences’ reported by race, ethnicity in transplant rates for MASH-HCC

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By Kate Burba

BOSTON — Hispanic and Asian patients with metabolic dysfunction-associated steatohepatitis and hepatocellular carcinoma were less likely to undergo liver transplantation compared with other races and ethnicities, data showed.

“MASH-HCC rates are much higher in our Hispanic patients and have surpassed hepatitis C-related HCC in 2019,” David W. Victor, MD, associate professor of clinical medicine at Houston Methodist Hospital, said at The Liver Meeting. Read the full article in Healio.

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Researchers Create App to Predict Whether Child in Acute Liver Failure Will Need Transplant

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By Kennedy Ferruggia, Assistant Editor

Children with a score of higher than 30 on the CHALF Score scale will need an emergency transplant.

In a new study conducted by Children’s Hospital Los Angeles (CHLA), researchers have developed a Children’s Hospital Los Angeles Acute Liver Failure (CHALF) Score that will help clinicians predict whether a child in acute liver failure will need a transplant or if they could recover.

Acute liver failure is defined as a rare condition in which the liver begins to lose ability to function. Read the full article in Pharmacy Times.

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Deprived Neighborhoods and Disparities in Access to Living Donor Kidney Transplantation

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By Victoria Socha

The optimal treatment for patients with end-stage kidney disease (ESKD) is living donor kidney transplantation, which offers improved health outcomes. Deprived neighborhoods are defined as those with low socioeconomic status, limited social cohesion, and reduced access to health care. According to Byoungjum Kim and colleagues, there are few data available on the role of neighborhood deprivation in assess to living donor kidney transplantation. Read the full article in DocWire News.

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Man given months to live becomes liver transplant pioneer

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By Ross Miklaszewicz

A charity worker who was given months to live has become the first patient in the world to receive a type of experimental liver transplant.

Adam Eisenberg, 58, from north London, was diagnosed with liver cirrhosis and non-alcoholic fatty liver disease.

When put on palliative care, he said he was effectively “sent home to die”.
Read the full story in BBC News.

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Daughter to mom who needed transplant at UI Health: ‘Don’t worry. I got your back’

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Raquel Ramirez shares her name with her daughter, so it was only fitting that one day her daughter would share a part of herself back with her mom.

When Ramirez got sick in 2021 and needed a liver transplant, her daughter, Raquel Regalado, who goes by Rocky, did not hesitate to be a living donor.

“They basically said, you’re in need of a transplant. We’re going to put you on the waiting list, but somebody can be a living donor,” Ramirez said. “She told me to my face: Don’t worry, Mom. I got your back.” Read the full story in UIC Today.

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Donor’s Immune Cells Could Help Transplant Recipients Avoid Organ Rejection

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By Amy Norton, HealthDay Reporter

MONDAY, Oct. 16, 2023 (HealthDay News) — A liver transplant can give people a new lease on life, but at the cost of lifelong immune-suppressing medication and its risks. Now an innovative approach to reduce, or possibly eliminate, certain patients’ reliance on those drugs is showing early promise.

The tactic is aimed at priming a transplant recipient’s immune system to better tolerate liver tissue from a living donor. A week before the transplant, the recipient receives an infusion of specific immune system cells from the donor — ones that, in theory, could tone down any immune system attack on the new “foreign” liver. Read the full article in U.S. News & World Report.

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Pain ‘exceedingly common’ among patients with cirrhosis before liver transplant

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By Robert Stott

VANCOUVER, British Columbia — Pain was reported in nearly 80% of patients with cirrhosis evaluated for liver transplant and, when paired with anxiety and depression, was a significant driver for poor quality of life, noted a presenter here.

“In my clinical work, I have always found it challenging to manage pain in patients with cirrhosis,” Jessica B. Rubin, MD, MPH, assistant professor of medicine in the division of gastroenterology and hepatology at University of California, San Francisco, told Healio.
Read the full story in Healio.

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Sarcopenia worsens liver transplant outcomes for patients with cirrhosis: Study

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By Lori Solomon

Sarcopenia is associated with adverse outcomes after liver transplantation (LT) in patients with decompensated cirrhosis (DC), according to a study published online Sept. 21 in the Journal of Cachexia, Sarcopenia, and Muscle.

Sarcopenia is associated with adverse outcomes after liver transplantation (LT) in patients with decompensated cirrhosis (DC), according to a study published online Sept. 21 in the Journal of Cachexia, Sarcopenia, and Muscle. Read the full article in Medical Xpress.

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From liver transplant to marathon, a veteran’s journey to the finish line

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By Tahleel Mohieldin

MILWAUKEE, Wisconsin (WTMJ) — Before the hugs and congratulations at the finish line, John Allison had a clear mission at the Milwaukee Lakefront Marathon Sunday.

Allison’s goal was to help raise awareness for veteran suicide and after finding an outlet for his own mental health struggles he wanted to encourage others to not give up. Read more in WQOW News 18.

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