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BP Control Beneficial for Liver Transplant Recipients

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— Patients who kept their blood pressure under 140/90 mm Hg had better kidney function at 1 year

WASHINGTON — Controlling blood pressure (BP) in liver transplant recipients led to better renal function at 1 year, post hoc data from a randomized trial suggested.

Recipients taking medication to control their BP had an estimated glomerular filtration rate (eGFR) that was 12.2 mL/min higher at 1 year when they were able to keep their BP below 140/90 mm Hg after liver transplant, reported Elizabeth Cabrera, MD, of Northwestern Memorial Hospital in Chicago. Read more in MedPage Today.

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Low Carb Diet Boosts Weight Loss for Liver Transplant Recipients With Obesity

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— LCD also positively impacted patients’ metabophenotype

Liver transplant recipients benefited from a low carbohydrate diet (LCD), achieving weight loss and an improved metabolic phenotype profile, according to a randomized trial.

In an interim analysis involving 27 patients, those who followed an LCD had a significantly higher mean weight loss of nearly 8 kg (about 17 lbs) over 6 months, compared to those on a low calorie restricted diet (CRD), who did not experience any significant weight loss (P=0.01), reported Mohammad Siddiqui, DO, of Virginia Commonwealth University in Richmond. Read more in MedPage Today.

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Transplanted Livers Can Survive Past 100

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These organs that live for more than a century could raise the age of potential donors, perhaps shortening waits for the life-saving procedure

Your liver could outlive you—even into the triple-digits, new research suggests.

Using the United Network for Organ Sharing’s organ transplant database, scientists assessed the ages of 253,406 livers transplanted between 1990 and 2022. Their analysis revealed that 25 of them had survived for more than 100 years.  Read the full article in Smithsonian Magazine.

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Some Donor Livers Keep Working for 100 Years: Study

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By Dennis Thompson, HealthDay Reporter

TUESDAY, Oct. 18, 2022 (HealthDay News) — Some human livers are tougher than others, lasting more than 100 cumulative years between the organ’s original host and a transplant recipient, a new study discovers.

Understanding what makes these livers so resilient could help improve the donor pool by paving the way for expanded use of livers from older donors, the researchers said.
Read the full story in U.S. News & World Report.

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Living donor transplantation offers a safe alternative for liver transplant patients

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Living donor liver transplants can reduce waitlist time and deaths according to a new study published in the Journal of Hepatology

Newswise — Amsterdam, September 26, 2022 – Demand for donor livers for transplant patients outstrips supply with over 15% of waitlist patients dying after a year. A new international study offers support for increasing the use of living donor liver transplantation (LDLT) in Western countries and reducing the imbalance between organ supply and demand. This study is reported in the Journal of Hepatology, the official journal of the European Association for the Study of the Liver, published by Elsevier.
Read more in Newswise.

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Donating Portion of Your Liver to Someone in Need Is Safe, Life-Saving: Study

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TUESDAY, Sept. 27, 2022 (HealthDay News) — Thousands of people die every year while waiting for a liver transplant. Living-donor transplantation holds the potential to save many of these lives, yet remains underused in the United States.

During the procedure, a portion of a donor’s liver is removed and transplanted into a person with liver disease. The donor’s remaining liver returns to its normal size and capacity within a few months. Read the full story in U.S. News & World Report.

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Everything You Need to Know About Being a Living Liver Donor

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With over 105,000 people on the national transplant waiting list, it should be no surprise that organ donation is one of the most important medical procedures of our time. In 2021 alone, more than 11,800 people on the national transplant list were waiting specifically for a liver transplant.

But what does the journey of a liver transplant involve, exactly? And what does this process look like for living liver donors who make the choice to donate a part of their liver?
Read more from Healthline.

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Study reports improvement in pediatric liver transplant outcomes over past decades

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Study Rundown: Outcomes in pediatric liver transplantations have improved over the course of the last few decades. This study aimed to evaluate patient characteristics, indications for pediatric liver transplant, and outcomes in a larger cohort of approximately 14,500 patients who underwent pediatric liver transplant in Europe prior to 18 years of age. Read more in 2 minute medicine.

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Father’s Life is Saved after Receiving Heart, Kidney and Liver Transplant

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Triple organ transplant is first in the nation to use three organs from a donor after circulatory death using innovative approach for organ recovery

Anthony Donatelli, age 40, has served in the U.S. Navy for 22 years. On February 14, 2022, he was wheeled into the operating room at UC San Diego Health; his body facing a different kind of combat. His kidney, heart and liver were failing, and he was about to receive three new organs.

“I didn’t have the option of dying. I had two children at home, a six and three-year-old,” said Donatelli. Read the full story from UC San Diego Health.

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Concurrent Liver Diseases See Increase Among Adult Liver Transplant Recipients

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New findings suggest concurrent liver diseases are increasing among adult liver transplant recipients in Australia and New Zealand, but do not seem to affect posttransplant survival.

The data additionally suggest these increases were predominantly driven by an increase in metabolic-associated fatty liver disease and alcohol-related liver disease. Read more in HCP Live.

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