Mayo Clinic performs first ever robot-assisted kidney transplant

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By Cathy Wurzer and Aleesa Kuznetsov


It is a full circle moment for Mayo Clinic. Next week will be the 60th anniversary of the clinics first kidney transplant from a living donor.

Now 60 years later, the clinic has performed it’s first robot-assisted kidney transplant.

On Oct. 4, a woman in her 60s received a kidney from her daughter. Dr. Timucin Taner is the division chair of Transplant Surgery at Mayo Clinic. Read the full article in MPR News.

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Kidney Week Roundup: Cell Therapy Cuts Immunosuppressive Drug Use Post-Transplant

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— Plus: bardoxolone methyl for diabetic kidney disease and spironolactone in hemodialysis patients

By Kristen Monaco

PHILADELPHIA — Some of the latest research in the field of nephrology presented at the American Society of Nephrology’s Kidney Week included sparsentan in focal segmental glomerulosclerosis, combination treatment with an SGLT2 inhibitor and an endothelin A receptor antagonist, and a novel aldosterone synthase inhibit in chronic kidney disease. Below are a few more highlights.
Read the full story in MedPage Today.

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Sparsentan Failed to Preserve Kidney Function Over Time in FSGS

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— However, more patients on the drug achieved partial remission of proteinuria vs irbesartan

By Kristen Monaco

PHILADELPHIA — Treatment with sparsentan (Filspari) led to no significant differences in estimated glomerular filtration rate (eGFR) slope compared with irbesartan among patients with focal segmental glomerulosclerosis (FSGS), the phase III DUPLEX trial showed.
Read the full article in MedPage Today.

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Male Kidney Donors Recover Kidney Function Faster than Female Counterparts

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By Abigail Brooks, MA

Data presented at ASN Kidney Week 2023 suggested male kidney donors recover greater kidney function than females after donation.

Male kidney donors may experience greater kidney function recovery than females after donation, according to findings presented at the American Society of Nephrology Kidney Week 2023.

Despite similar predonation estimated glomerular filtration rate (eGFR) between male and female participants, males showed a significantly greater eGFR recovery than females through 24-month follow-up (P = .003), highlighting a potential need for sex-specific evaluation, counseling, and monitoring among kidney donors.1 Read the complete article in HCP Live.

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Multicomponent Intervention Fails to Improve Access to Kidney Transplantation

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By Abigail Brooks, MA

EnAKT LKD was conducted across 26 CKD programs in Ontario Canada, offering a multi-component intervention designed to target several barriers thought to prevent kidney transplantation and living donation – however, results showed no significant difference between the intervention and usual care groups.

Results from the Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) trial showed evidence of intervention uptake but no difference in steps completed toward kidney transplantation between the intervention and usual-care groups.
Read the full article in HCP Live.

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Could kidney transplant patients be spared a lifetime of immunosuppressants?

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By Annalisa Merelli

Kidney transplants are the most common organ transplant procedure in the U.S., with 25,000 taking place in 2022. But for patients who receive new kidneys, the transplant is often followed by severe lifelong challenges, many of which are linked to the immunosuppression drug regimen required after surgery to ensure the body does not reject the new organ. These treatments have side effects and toxicities that impact patients’ long-term health, and even survival, leading to a transplant failure rate of 30-50% at the 10-year mark. Read the full article in STAT.

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Mortality, failure rates similar in donors with high vs. low kidney donor profile index

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By Shawn M. Carter

PHILADELPHIA — Kidneys from adults with a high kidney donor profile index may boost transplantation access, but a multidisciplinary method can bring positive results in groups with low deceased kidney donor transplant rates, a speaker said.

“We treat patients in a predominantly Black community in Brooklyn,” where there may be less access to required medical resources, Fausto Ricardo Cabezas, MD, of SUNY Downstate Health Sciences University in New York, told Healio of research he conducted with his team and that was presented at ASN Kidney Week. Read the full article in Healio.

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Early kidney disease detection can cut down wait time for transplant

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By Kara Willis

HOUSTON (KIAH) — Over 37 million Americans are living with kidney disease. Once someone reaches the kidney failure stage, patients either go through dialysis treatment or wait for a transplant.

Sadly, there’s a shortage of kidney transplants and that is causing longer wait times for patients to be paired with a new kidney. Davita Horizon Dialysis says that nine in 10 people are unaware that they have kidney disease until they reach a more advanced stage or reach kidney failure. Check out the full story from CW 39 Houston.

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Kidney transplantation turns back the clock on renal aging

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By Tarun Sai Lomte

In a recent study published in the Journal of Internal Medicine, researchers observe that kidney transplantation (KT) mitigates the effects of renal aging.

Treating chronic kidney disease

Chronic kidney disease (CKD) is an age-related disease and exhibits an accelerated aging phenotype. The reduced clearance of uremic toxins during CKD results in the accumulation of toxic solutes that contribute to endothelial dysfunction, chronic inflammatory burden, and increased oxidative stress. Read the full article in News Medical Life Sciences.

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