‘I Can’t Wait to Swim!’ | How a Kidney Transplant Changed the Possibilities for 4-Year-Old Stella

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“She has so much more energy and is eating so much more. She is also moving and walking more than she ever did.”

Four-year-old Stella Allison has always loved telling jokes and playing dress up.

With energy that is contagious and a smile that lights up a room, her mom Kyley Barthlow says Stella has grown into a high-spirited and chatty child – but was born a real fighter.
Read the full story from Seattle Children’s.

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Post-Kidney Transplant MACE Predicts Worse Survival

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Recently reported study findings provide a detailed look at how a major adverse cardiovascular event (MACE) after kidney transplantation adversely affects survival and identify which patients are at elevated risk for MACE. Data also demonstrate that patients who receive a kidney transplant are at lower MACE risk compared with those who remain on dialysis.  

In a study of 30,325 KTRs in England published in Kidney International, a MACE occurred in 781 within the first year of transplantation surgery. Read more in Renal & Urology News.

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Patients without HCV can take transplants from donors with HCV without risking graft survival

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Transplanting kidneys from donors who have the hepatitis C virus into patients who are HCV-negative is not associated with increased risk for early graft failure, according to a presentation at the American Transplant Congress.

“With the excellent outcomes of the new therapy of hepatitis in the last few years, we intend to examine the kidney transplant outcomes using kidneys from donors with hepatitis C,” Tarek Alhamad, MD, MS, the medical director of kidney transplantation at Washington University, told Healio. Read more in Healio.

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Infliximab may lead to higher infection rate, no improvement in transplant outcomes

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The use of infliximab in patients with a deceased donor kidney transplant led to increased infections and did not improve allograft survival, according to data presented at the American Transplant Congress.

“The intervention had no effect on allograft function or acute rejection,” Peter S. Heeger, MD, a professor of medicine and immunology at the Icahn School of Medicine at Mount Sinai Medical Center in New York, told Healio. “Unexpectedly, we observed higher rates of infection with the BK virus, a virus that can contribute to graft dysfunction and graft loss.”
Read the full article in Healio.

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Diabetes in Kidney Transplant Recipients Ups Risk for Overall Graft Loss

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Type 2 diabetes in kidney transplant recipients (KTRs) is associated with an increased risk for overall graft loss, with the increased risk due to death with a functioning graft, according to study findings presented at the 2022 American Transplant Congress (ATC 2022) in Boston, Massachusetts.

Vinayak Rohan, MD, of the Medical University of South Carolina in Charleston, and colleagues conducted a longitudinal study of 233,703 KTRs using 2002-2018 data from the Scientific Registry of Transplant Recipients. Read more in Renal & Urology News.

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New research looks at racial disparities in kidney transplants

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CINCINNATI — African Americans wait two- to four-times longer on transplant waiting lists than whites, according to the Cleveland Clinic. One health center is working to get answers and cut down the wait.

D’On Ingram received an ultrasound as a follow up to his recent kidney transplant—a surgery that was years in the making. Just 10 years ago, doctors diagnosed him with stage three renal failure. Five years later, his kidneys got weaker, and his doctor put him on dialysis.  Read the full story in Spectrum News 1 here.

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Living organ donations save lives. This is how you become a donor

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(CNN) Samira Jafari is at home now resting from a surgery that saved a life — not her own, but her colleague’s.

The deputy managing editor of CNN’s investigations unit answered the request for employees to be tested to find a donor for Senior UN Correspondent Richard Roth, who needed a kidney transplant, and found that her blood and tissue was a match.
Read the full story from CNN Health.

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Older living kidney donor age may be negative predictor of recipient, graft survival

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Compared with living donors aged 50 to 70 years, donor age older than 70 years may be a negative predictor of kidney transplant and graft survival, according to a presentation at the American Transplant Congress.

“I set out to see if the data and outcomes of a national cohort met my anecdotal findings that living kidney donor transplants from donors [older than] 70 years don’t perform as well compared to their younger donor counterparts regardless of measured donor GFR and noted that this had not been studied in a contemporary cohort in the past 10 years,” Adam Bregman, MD, MBA, an assistant professor of medicine in the division of nephrology and hypertension at the University of Minnesota, told Healio. Read more in Healio.

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