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Walking more than 10,000 steps daily reduces mortality risk in prediabetes and diabetes

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Adults with prediabetes or diabetes have a reduced risk for all-cause mortality if they walk more than 10,000 steps per day, according to study findings published in Diabetes Care.

“Physical activity is very beneficial for patients with diabetes and prediabetes,” Jesús Del Pozo-Cruz, PhD, associate professor in the department of physical education and sport at the University of Seville in Spain, told Healio. “We provide the optimal number of steps per day to improve long-term health in these patients.” Read the full story in Healio.

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Inflammation a Culprit in Long COVID Heart Problems

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— Prospective study illuminates mechanisms of lingering heart issues after mild COVID-19

While long COVID holds many mysteries, researchers found clues to the heart symptoms common in these patients, which pointed to ongoing inflammation as the mediator.

In a cohort of 346 previously healthy patients with initially mild COVID-19, most seen for lingering symptoms a median of around 4 months later, structural heart disease and elevated biomarkers for cardiac injury or dysfunction were rare. Read the full story in MedPage Today.

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US records milestone 1 millionth organ transplant

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The first successful transplant was performed in 1954 in Boston.


The United States recorded its one millionth organ transplant Friday afternoon, a historic milestone for the medical procedure that has saved thousands of lives.

The record achievement was confirmed at 12:50 p.m. ET by the United Network for Organ Sharing, a nonprofit that runs the only organ procurement and transplantation network in the country. Check out the full story from ABC News here.

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CareDx Demonstrates Global Leadership at 29th International Congress of The Transplantation Society

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Over 25 Abstracts Highlight Value of AlloSure and AlloSeq cfDNA

BRISBANE, Calif.–(BUSINESS WIRE)– CareDx, Inc. (Nasdaq: CDNA) – The Transplant Company™ focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers – today announced its leading participation in the 29th International Congress of The Transplantation Society (TTS 2022) taking place September 10-14 in Buenos Aires, Argentina.

Transplant physicians will present data from over 25 abstracts demonstrating the value of AlloSure® donor-derived cell-free DNA (dd-cfDNA) and AlloSeq cfDNA in clinical practice, and emerging trends and innovation in transplantation, including artificial intelligence and the potential use of CareDx’s molecular testing services for xenotransplantation surveillance. Read the complete press release on CareDx.com.

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Influence of organ quality on the observed association between deceased donor kidney procurement biopsy findings and graft survival

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Deceased donor kidney procurement biopsies findings are the most common reason for kidney discard. Retrospective studies have found inconsistent associations with post-transplant outcomes but may have been limited by selection bias because kidneys with advanced nephrosclerosis from high-risk donors are typically discarded.
Read the full abstract from Wiley Online Library.

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2022 Donate Life Transplant Games of America in San Diego, CA

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CareDx recently had the honor of being the Presenting Sponsor of the 2022 Transplant Games of America in sunny San Diego. Every two years the Transplant Games brings together thousands of members of the transplant community, from transplant recipients, living donors, donor families, to individuals on the wait list, caregivers, and transplant professionals, to partake in an Olympic style event for the world’s largest celebration and testimony to the gift of life.  Check out the recap story on CareDx.com.

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Report cites health inequity, disconnect with primary care as barriers for treating CKD

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A new report from the Milken Institute recommends that health officials prioritize identification of the root causes of health inequity that contribute to kidney disease in efforts to slow down its occurrence.

“Tackling this public health issue requires a whole-of-society effort, and in this report, we call on policymakers (federal, state and local), government agencies, health care administrators, health care providers, allied health professionals, payers, members of the community and community-based organizations (CBOs) to assume leadership and supporting roles and to collaborate with intention and urgency across public health, health delivery and nontraditional health sectors,” Sarah Wells Kocsis, MBA, director of the Milken Institute’s Center for Public Health and colleagues wrote in the report.
Read the full story from Healio.

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Dementia Risk Tied to Daily Step Count

Photo by Arek Adeoye on Unsplash
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— Incident dementia dropped by 25% with as little as 3,800 steps per day, study found

A daily total of 3,800 to 9,800 steps was tied to lower dementia risk, longitudinal data from the U.K. Biobank showed.

The optimal dose of daily steps — the value with the highest dementia risk reduction — was 9,826 steps (HR 0.49, 95% CI 0.39-0.62), according to Borja del Pozo Cruz, PhD, of the University of Southern Denmark in Odense, and colleagues. Read more in MedPage Today.

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Father’s Life is Saved after Receiving Heart, Kidney and Liver Transplant

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Triple organ transplant is first in the nation to use three organs from a donor after circulatory death using innovative approach for organ recovery

Anthony Donatelli, age 40, has served in the U.S. Navy for 22 years. On February 14, 2022, he was wheeled into the operating room at UC San Diego Health; his body facing a different kind of combat. His kidney, heart and liver were failing, and he was about to receive three new organs.

“I didn’t have the option of dying. I had two children at home, a six and three-year-old,” said Donatelli. Read the full story from UC San Diego Health.

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