JACC Publication Guides Use of CareDx’s HeartCare Transplant Rejection Surveillance in Clinical Practice

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JANUARY, 26, 2023

Guide Helps Transplant Centers Continue the Evolution from Endomyocardial Biopsies to Noninvasive Surveillance Using AlloMap GEP and AlloSure dd-cfDNA

BRISBANE, Calif.–(BUSINESS WIRE)– CareDx, Inc. (Nasdaq: CDNA) – The Transplant Company™ focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers – today announced that the Journal of the American College of Cardiology (JACC): Heart Failure has published a detailed guide1 to help clinicians transition from routine invasive endomyocardial biopsy (EMB) to a less invasive acute rejection monitoring protocol in clinical practice.

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Kidney Transplant Recipients Do Not Benefit From Infliximab Induction

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Infliximab induction therapy fails to protect kidney transplants and appears to increase the risk of BK virus infection in recipients, investigators report.

Peter Heeger, MD, of the Comprehensive Transplant Center at Cedars Sinai Medical Center in West Hollywood, California, and colleagues randomly assigned 225 unsensitized recipients of deceased-donor kidneys to receive intravenous infliximab (3 mg/kg) or saline placebo prior to kidney reperfusion. Read the full story in Renal & Urology News.

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Researchers confirm successful rehabilitation and recovery of human donor lungs previously deemed unfit for transplant

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Study demonstrates that a novel technique for regenerating donor lungs can increase the number of organs available for life-saving transplantation

NEW YORK, Jan. 23, 2023 /PRNewswire/ — A novel method for supporting and recovering donor lungs outside the body shows potential to increase the number of organs available for transplant, according to a recent study published in The Journal of Heart and Lung Transplantation. Read the complete press release on Yahoo.com.

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Widely used test kept Black people from getting kidney transplants sooner. Now that’s changing.

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Kristal Higgins just wants to be healthy, become a nurse and travel to Greece. But she has kidney failure and has been on a transplant waiting list for six years. 

The disease and its comorbidities have touched many of her loved ones. Her mother has stage 2 kidney disease. Her father is diabetic, a risk factor for kidney failure, as was her late grandmother. Several of her relatives have kidney failure. Read more in USA Today.

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Kidney Transplant Outcomes in Recipients Over the Age of 70

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Published: January 20, 2023 (see history)

Cite this article as: Mehta J, Ndubueze O, Tatum D, et al. (January 20, 2023) Kidney Transplant Outcomes in Recipients Over the Age of 70. Cureus 15(1): e34021. doi:10.7759/cureus.34021


Abstract

Background: Patients older than 70 years are the fastest-growing age group of patients requiring renal replacement therapy. This has resulted in a corresponding increase in the number of elderly transplant recipients. We hypothesized that graft survival in this population would be comparable to that seen in the literature on kidney transplant recipients under 70 years of age. Read the complete abstract in Cureus.

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Neurological effects of long COVID: It is ‘not only a respiratory disease’

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As the world continues to grapple with effects of the COVID-19 pandemic, individuals around the globe are still dealing with symptoms of SARS-CoV-2 infection for months, even years, after their initial infection.

Post-acute sequelae of COVID-19, more commonly referred to as long COVID, are defined by the CDC as a wide range of new, returning or ongoing health issues that people experience after being infected with SARS-CoV-2, the virus that causes COVID-19.
Read more from Healio.

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