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Physicians Transplant Kidneys into Children Without Immune Suppressing Drugs

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​Three pediatric patients with a rare genetic disease that causes kidney failure have successfully been treated with transplanted kidneys without using anti-rejection drugs or treatments.

Experts at Stanford University treated three children with a rare condition called Schimke immuno-osseous dysplasia (SIOD). This genetic condition not only causes a weakened immune system but also causes kidney disease, according to the Genetic and Rare Diseases Information Center at the NIH. Read more in Healthline.

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Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

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In a recent study posted to the medRxiv* pre-print server, Canadian researchers evaluated antibody responses in kidney transplant recipients (KTRs) before and one and three months after receiving the third dose of a messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine.
Read the full story in News Medical Life Sciences.

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Walking For Kidney Transplants

Photo by Arek Adeoye on Unsplash
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I have often been asked why I take such long walks. I was in my transplant doctor’s office a few months back. He gave me that look. You know the look. Like that look your Dad used too give you before the stern lecture was coming. The serious discussion lecture. He told me I was not getting enough exercise, and I should try to get out more. He suggested walking. I’ve never been an athlete. I have avoided exercise in the past. I’ve always been an academic. I hated gym class. But I knew he was right. I spend a lot of time on my computer or phone. I’m known for my dedication (some have called it an addiction) to social media. As the proud recipient of AAKP’s inaugural National Social Media Education & Advocacy Award and as developer of 60 Kidney Pages and 50 Kidney Group pages, as well as nine electronic newspapers and 10+ blog sites, I knew my time online wasn’t going to slow down – but  I also knew I had to get out and move more. But in my mind, it had to mean something more than just exercise for me to commit to long-term.
Read the full article from the American Association of Kidney Patients (AAKP).

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Organ procurement and transplant board votes to establish race-neutral eGFR equation

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The Organ Procurement and Transplant Network Board of Directors has unanimously voted to remove the race coefficient from eGFR equations.

Several organizations have called for the removal of the race coefficient because it puts Black patients on the transplant list at a disadvantage. Following the vote by its board, the Organ Procurement and Transplant Network (OPTN) will be implementing a race-neutral eGFR equation within 30 days. Read the full story in Healio.

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CV complications of COVID-19 vary widely; patients with HF at high risk

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PHILADELPHIA — The CV complications of COVID-19 are wide-ranging, and the consequences can be especially serious in patients with HF, a speaker said at the Heart in Diabetes CME conference.

The presentation by Lee R. Goldberg, MD, MPH, FACC, section chief of advanced cardiac failure and heart transplant, vice chair for medicine informatics and professor of medicine at the University of Pennsylvania, covered a number of topics related to cardiac complications of COVID-19. Read the full article in Healio.

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CareDx Lead Sponsor for 2022 Donate Life Transplant Games

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CareDx’s Mobile Health App, AlloCare, is the Official App for the Games

SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Jun. 28, 2022– CareDx, Inc. (Nasdaq: CDNA) – The Transplant Company™ focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers – today announced its participation and presenting sponsorship for the 2022 Donate Life Transplant Games taking place July 29 to August 3, 2022, in San Diego, California. CareDx’s transplant patient health app, AlloCare®, is the official app for the Games. Read the full press release here.

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For some desperate COVID patients, lung transplants are the best chance at survival

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Dennis Franklin thought he had come down with a cold when he was vacationing with his wife in Holden, Mo., in June 2021. Too tired to do anything, he cut the trip short.

Once home in St. Charles, Mo., he went to an urgent care center and was diagnosed with COVID-19 and pneumonia. Two days later, on his wedding anniversary, he didn’t wake up. When his wife, Julia, tried to rouse him, she realized he was barely breathing. She frantically called 911 and an ambulance rushed him to the local hospital. Read the full story in the Pittsburgh Post-Gazette here.

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Study finds racial and ethnic disparities in cardiac rehabilitation participation regardless of income

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Participation in cardiac rehabilitation is low among Asian, Black and Hispanic adults compared to white adults, with significant disparities by race/ethnicity regardless of income, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

Cardiac rehabilitation programs combine physical activity with counseling about healthy living and stress reduction to help improve recovery after a major cardiovascular event, such as a heart attack, heart failure, heart surgery or angioplasty.
Read more in News Medical Life Sciences.

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A new storage technique could vastly expand the number of livers available for transplant

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It allows donor livers to be held for days—significantly longer than the standard now–and even treated if they are damaged.

A patient who received a donated liver that had been stored for three days in a new type of machine that mimics the human body is healthy one year on from surgery, according to a study in Nature Biotechnology. The technology could significantly increase the number of livers suitable for transplant, the authors claim, both by enabling donor livers to be preserved for longer than the current standard and by making it possible to repair organs that are available but too damaged to transplant as is.
Read more in MIT Technology Review.

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