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Liver transplantation linked to lower antibody, T-cell response to COVID-19 vaccine

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LONDON — Patients who received a liver transplant had significantly reduced antibody and T-cell responses to SARS-CoV-2 vaccination compared with healthy controls, according to research presented at the International Liver Congress.

“Emerging data have demonstrated suboptimal immune responses to SARS-CoV-2 vaccination in immunosuppressed cohorts,” Thomas Marjot, a clinical research training fellow at the Oxford Liver Unit at Oxford University Hospitals NHS Foundation Trust, and colleagues wrote. Read more in Healio.

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Effects of exercise in renal transplant recipients

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Even after a successful renal transplantation, the renal transplant recipients (RTRs) keeps on suffering the consequences of the uremic sickness. Cardiovascular risk, work capacity, and quality of life do not improve according to expectations since biological and psychological problems are not completely solved by pharmacological treatment.
Read more in the World Journal of Transplantation here.

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Kidney Transplant Survival Benefit Greater for Patients on Dialysis

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Deceased donor kidney transplantation (DDKT) confers a greater survival benefit to adult waitlist candidates on dialysis than those managed preemptively, investigators reported at the 2022 American Transplant Congress (ATC 2022) in Boston, Massachusetts.

The current US Kidney Allocation System (KAS) allows for DDKT candidates not yet on dialysis to accrue waiting time points by listing at a transplant center with a low estimated glomerular filtration rate. Read the full story in Renal & Urology News.

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Do you need support?

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You aren’t alone! Talk to someone who’s been there.

What is NKF PEERS?

NKF PEERS is a peer mentoring program, where kidney patients are connected via phone with trained mentors who have been there themselves. Peer mentors can share their experiences with dialysis, transplant, or living kidney donation with you. 
Learn more about NKF Peers from the National Kidney Foundation.

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Insights on Long COVID Care

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— Fernando Carnavali, MD, discusses helping patients adjust to being chronically ill

In this video, Fernando Carnavali, MD, of Mount Sinai’s Center for Post-COVID Care in New York City, discusses the strategies for managing long COVID and what we still don’t know about this often debilitating condition.

The following is a transcript of his remarks:

The population of post-COVID, long COVID, has changed over time. I think that one of the most significant changes is that the population is more aware of these chronic conditions, and I think that the uncertainties are still there.
Watch the video and read the transcript on MedPage Today here.

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Is It the Right Time for a Paradigm Shift in Mental Health Care Delivery?

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— New review highlights evidence for a community-based approach

NEW ORLEANS — Mental health care delivery needs a paradigm shift, according to a review that was published in the American Journal of Psychiatry and presented at the American Psychiatric Association (APA) annual meeting.

Mental health professionals should move from an individual therapy and pharmacological treatment-focused approach to a community-level, public mental health-focused approach to achieve a more equitable model of mental health care, said Margarita Alegría, PhD, of Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues.
Read the full story in MedPage Today.

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Fewer Headache Days With Acupuncture

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— Chronic tension headache patients experience relief with 8-week treatment course

Acupuncture helped reduce the frequency of chronic tension-type headaches (CTTH), a randomized controlled trial in China found.

More than two-thirds (68.2%) of people with CTTH who received true acupuncture reported at least a 50% reduction in the number of monthly headache days at week 16, compared with 48.1% who had superficial acupuncture (OR 2.65, 95% CI 1.5-4.77), reported Ying Li, MD, PhD, of Chengdu University of Traditional Chinese Medicine in China, and colleagues in Neurology. Read the full story in MedPage Today.

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Racial disparities strongest among young adults on home dialysis, transplant recipients

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Racial and ethnic disparities in kidney replacement therapies were most pronounced among patients aged 22 to 44 years who are either transplant recipients or on home dialysis, according to data in the American Journal of Kidney Diseases.

“Research has shown wide racial and ethnic disparities in use of kidney transplant and home dialysis, yet how age interacts with these disparities is unknown,” Adam S. Wilk, PhD, and colleagues wrote. Read more in Healio.

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Transplantation within 7 days of listing boosts survival in acute-on-chronic liver failure

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LONDON — Early liver transplantation within 7 days of listing was linked to improved 90-day and 1-year survival among patients with grade 3 acute-on-chronic liver failure, according to data presented at the International Liver Congress.

“Currently, the ideal time frame between listing and liver transplantation to achieve optimal patient outcome in [grade 3 acute-on-chronic liver failure] is not known,” Joseph J. Alukal, MD, of Platinum Hospitalists and Spring Valley Hospital Medical Center in Nevada, told Healio. Read more in Healio.

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