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Stanford Medicine student devises liver exchange, easing shortage of organs

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A rare three-way exchange of liver transplants in Pakistan was made possible with a new algorithm developed by a Stanford Medicine student.

December 7, 2022 – By Nina Bai

In some countries, cultural norms limit the availability of organs from deceased donors. An algorithm devised by Stanford Medicine’s Alex Chan can increase the number of transplants through a liver exchange.
Marko Aliaksandr/Shutterstock.com

On March 17 of this year, six operating rooms at the Pakistan Kidney and Liver Institute were prepped for six simultaneous surgeries. On three operating tables were patients with end-stage liver disease. On the other three were their relatives — a daughter, a son and a wife — who had agreed to donate a portion of their livers. Read more from Stanford Medicine News Center.

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Guidelines updated for managing diabetes with high risk for hypoglycemia

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The Endocrine Society released updated clinical practice guidelines that account for new technology and newer forms of insulin and glucagon in the management of diabetes-related hypoglycemia.

These recommendations, published in The Journal of Clinical Endocrinology & Metabolism, are updates from the Endocrine Society’s 2009 inpatient hypoglycemia guideline. Read more in Healio.

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A pivotal moment for the organ donation and transplant community

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McBride addresses public concerns, calls for collaboration and shares vision for the future

By Maureen McBride, Ph.D., Interim UNOS CEO

This morning, I delivered remarks before the Organ Procurement and Transplantation Network (OPTN) Board of Directors in St. Louis during our semi-annual meeting. In them, I outlined my vision for community-wide efforts in the days, weeks, and months to come. I discussed critical issues facing the national system and how we can move forward together, acknowledging where we must improve, challenges we must address, and opportunities we must identify to best serve patients.

To read her complete remarks, read the blog from UNOS.

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Flu hospitalizations hit 12-year high for this time of year

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Hospitalizations for influenza are the highest they have been at this time of year since 2010, the CDC reported Friday.

There have been at least 8.7 million illnesses, 78,000 hospitalizations and 4,500 deaths from influenza so far this season in the United States, according to the CDC, with hospitalizations doubling over the course of a week to 19,593 patients in the week ending Nov. 26. Read more in Healio.

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‘A gift of life’: the NHS double lung transplant that saved Covid patient

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After months in intensive care, Cesar Franco became the first person in Britain to have the operation because of the virus

“When I woke up I was confused. I remembered the doctors in St George’s hospital deciding to intubate me. But when I woke up from the intubation, I’d been transferred to another hospital, St Thomas’, and was on a machine that was keeping me alive. I wondered how things had gotten so bad and how I’d gone from being just ill to being, you know, very close to dying.”
Read the story in The Guardian here.

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Greater adherence to plant-based Portfolio diet cuts risk for developing type 2 diabetes

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Women who adhered more to a plant-based Portfolio diet lowered their risk for developing type 2 diabetes, according to findings from the Women’s Health Initiative published in Diabetes Care.

“There are two main takeaways from this study,” Andrea Glenn, PhD, RD, a postdoctoral research fellow in the department of nutrition at the Harvard T.H. Chan School of Public Health and in the department of nutritional sciences at the University of Toronto, told Healio. Read the full story in Healio.

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Questions remain on patient costs, formulary for expanded immunosuppressive drug benefit

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Demand for transplantation has rapidly increased around the world during the past decade due to an increase in incidence of comorbidities leading to organ failure along with a rise in longevity in patient years.

This increase in demand has outpaced current graft survival and resulted in the need for re-transplantation – and for more organs. Consequently, there has been a major increase in the number of patients on transplant waitlists, as well as an increase in the number of patients dying waiting for a transplant. Read more in Healio.

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Organ donation, transplant rates increase during motorcycle rallies

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An analysis by Harvard Medical School and Massachusetts General Hospital researchers shows steep increases in organ donations and transplantations take place during large motorcycle rallies.

The research, published in JAMA Internal Medicine, shows that in the regions where the seven largest motorcycle rallies were held throughout the United States between 2005 and 2021, there were 21% more organ donors per day, on average, and 26% more transplant recipients per day, on average, during these events, compared with days just before and after the rallies, according to a press release. Read the full story in Healio.

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